Skin Cutaneous Melanoma

Description

MalaCards based summary: Skin Melanoma, also known as cutaneous melanoma, is related to melanoma, cutaneous malignant 8 and tumor predisposition syndrome, and has symptoms including exanthema and pruritus. An important gene associated with Skin Melanoma is TYR (Tyrosinase), and among its related pathways are Oncogene Induced Senescence and Thyroid cancer. The drugs interferon alfa-2b and procarbazine have been mentioned in the context of this disorder. Affiliated tissues include skin, lymph node and brain, and related mouse phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and hearing/vestibular/ear.

Disease-associated SNP
Dissease-associated Gene
Disease-associated LncRNA
Lncrna ID Location SNP Protein Option
ENST00000423728.4 chr1:494876-499175 - FGF2, NRAS
ENST00000422528.1 chr1:760911-761989 - CDKN1A
ENST00000585745.4 chr1:784370-795513 - NME1, MITF, CDKN2B
ENST00000593022.4 chr1:784370-806459 - CDKN2A, TP53
ENST00000416570.4 chr1:827699-852766 - CASP3, ERBB2
ENST00000607769.1 chr1:904834-915976 - PTGS2
Current Page is
Co-expression Network:
If the number of edges is greater than 100k, we provided the graph containing 85k edges.