Pheochromocytoma:MalaCards based summary: Pheochromocytoma, also known as sporadic pheochromocytoma/secreting paraganglioma, is related to paragangliomas 4 and von hippel-lindau syndrome, and has symptoms including proteinuria, congenital cataract and episodic hypertension. An important gene associated with Pheochromocytoma is SDHB (Succinate Dehydrogenase Complex Iron Sulfur Subunit B), and among its related pathways are Carbon metabolism and Pyruvate metabolism and Citric Acid (TCA) cycle. The drugs metyrosine and propranolol have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, testes and thyroid, and related mouse phenotypes are Decreased sensitivity to paclitaxel and Decreased viability.
Paragangliomas:MalaCards based summary: Paragangliomas 4, also known as sdhb-related hereditary paraganglioma-pheochromocytoma syndrome, is related to hereditary paraganglioma-pheochromocytoma syndromes and neuroblastoma, and has symptoms including neuroblastoma, gastrointestinal stroma tumor and obsolete pulsatile tinnitus (tympanic paraganglioma). An important gene associated with Paragangliomas 4 is SDHB (Succinate Dehydrogenase Complex Iron Sulfur Subunit B). Affiliated tissues include endothelial, thyroid and lung.