Liver Hepatocellular Carcinoma

Description

MalaCards based summary: Hepatocellular Carcinoma, also known as liver cancer, is related to glomerulonephritis and plasmacytoma, and has symptoms including hepatocellular carcinoma, micronodular cirrhosis and subacute progressive viral hepatitis. An important gene associated with Hepatocellular Carcinoma is AXIN1 (Axin 1), and among its related pathways are Pathways in cancer and Apoptosis Pathway. The drugs interferon alfa-2b and recombinant interferon beta-1a have been mentioned in the context of this disorder. Affiliated tissues include the liver, liver and lung, and related mouse phenotypes are Increased shRNA abundance (Z-score > 2) and cellular.

Disease-associated SNP
Dissease-associated Gene
Disease-associated LncRNA
Lncrna ID Location SNP Protein Option
ENST00000469289.1 chr1:30267-31109 - PLPP5, RBM39, ADAM17, EGF, LARP1
ENST00000471248.1 chr1:110953-129173 - IGF2, ARG1, CDK4, RUNX3, HFE
ENST00000484859.1 chr1:141474-149707 - FASLG, RBM39, JUN, HEPACAM
ENST00000442116.1 chr1:257864-264733 - CDKN1B, CD81, KRT8, IGF2, SKP2
ENST00000431321.1 chr1:365389-366120 - PNLIPRP3, EGF, AXIN1
ENST00000613471.1 chr1:476738-489710 - PINX1, STARD13, G6PC, SMAD3, VPS37A
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Co-expression Network:
If the number of edges is greater than 100k, we provided the graph containing 85k edges.