Head and Neck Squamous Cell Carcinoma


MalaCards based summary: Squamous Cell Carcinoma, Head and Neck, also known as squamous cell carcinoma of the head and neck, is related to herpes simplex and nasopharyngeal carcinoma, and has symptoms including squamous cell carcinoma, coughing and halitosis. An important gene associated with Squamous Cell Carcinoma, Head and Neck is PTEN (Phosphatase And Tensin Homolog), and among its related pathways are HIF1Alpha Pathway and Transcription Ligand-dependent activation of the ESR1/SP pathway. Affiliated tissues include lung, thyroid and skin, and related mouse phenotypes are Decreased viability in esophageal squamous lineage and liver/biliary system.

Disease-associated SNP
Dissease-associated Gene
Disease-associated LncRNA
Lncrna ID Location SNP Protein Option
ENST00000469289.1 chr1:30267-31109 - EGF
ENST00000471248.1 chr1:110953-129173 - LOXL4, CDK4, FANCL, FANCE, CCND1
ENST00000484859.1 chr1:141474-149707 - LY6D, ING1, VEGFC
ENST00000442116.1 chr1:257864-264733 - ERBB3
ENST00000431321.1 chr1:365389-366120 - EGF, CD44
ENST00000613471.1 chr1:476738-489710 - MMP14
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Co-expression Network:
If the number of edges is greater than 100k, we provided the graph containing 85k edges.