Esophageal Carcinoma

Description

MalaCards based summary: Esophageal Cancer, also known as esophageal carcinoma, is related to gastric cancer and lung cancer, and has symptoms including weight loss, feeding difficulties in infancy and esophageal neoplasm. An important gene associated with Esophageal Cancer is TGFBR2 (Transforming Growth Factor Beta Receptor 2), and among its related pathways are Colorectal Cancer Metastasis and Endometrial cancer. The drugs methotrexate sodium and cisplatin have been mentioned in the context of this disorder. Affiliated tissues include lung, lymph node and testes, and related mouse phenotypes are endocrine/exocrine gland and liver/biliary system.

Disease-associated SNP
Dissease-associated Gene
Disease-associated LncRNA
Lncrna ID Location SNP Protein Option
ENST00000469289.1 chr1:30267-31109 - EGF, CHEK2
ENST00000471248.1 chr1:110953-129173 - CDK4, FSCN1, CCND1
ENST00000484859.1 chr1:141474-149707 - ALDH2, ERCC1, FASLG, CDX2, JUN
ENST00000442116.1 chr1:257864-264733 - CDKN1B, MUC1
ENST00000431321.1 chr1:365389-366120 - EGF, CD44
ENST00000613471.1 chr1:476738-489710 - CTAG1B
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Co-expression Network:
If the number of edges is greater than 100k, we provided the graph containing 85k edges.