Breast Invasive Carcinoma

Description

MalaCards based summary: Breast Cancer, also known as breast carcinoma, is related to familial breast cancer and estrogen-receptor negative breast cancer, and has symptoms including pelvic pain, lameness, animal and pain. An important gene associated with Breast Cancer is BRCA2 (BRCA2, DNA Repair Associated), and among its related pathways are Integrated Breast Cancer Pathway and Integrated Pancreatic Cancer Pathway. The drugs aminoglutethimide and epirubicin have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and lymph node, and related mouse phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Decreased homologous recombination repair frequency.

Disease-associated SNP
Dissease-associated Gene
Disease-associated LncRNA
Lncrna ID Location SNP Protein Option
ENST00000469289.1 chr1:30267-31109 - NAT2, STS, TIMP2, EGF, BCL2
ENST00000471248.1 chr1:110953-129173 - SNCG, IGF2, TOP1, BCAR4, FLT4
ENST00000484859.1 chr1:141474-149707 - CDH2, AREG, SFN, ANKRD30A, GPNMB
ENST00000442116.1 chr1:257864-264733 - CDKN1B, AKAP13, MUC1, KRT5, KRT8
ENST00000431321.1 chr1:365389-366120 - WNT10B, EGF, CD44, TSG101, FBLN1
ENST00000613471.1 chr1:476738-489710 - MKI67, XRCC3, PLAUR, STAT1, FLT4
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Co-expression Network:
If the number of edges is greater than 100k, we provided the graph containing 85k edges.